Part1. What is Horse Chestnut Extract powder?
Horse Chestnut Extract powder is a brownish-yellow powdery substance extracted from the dry and mature seeds of Aesculus Aesculus AesculuschinensisBge., Zhejiang Aesculus or AesculuswilsoniiRehd. The main active ingredient is aescin, which has anti-inflammatory properties , anti-exudation, anti-brain edema, anti-tumor and other effects.
Part2. Pharmacological effects
1. Anti-inflammatory and antibacterial effects
2. Cholesterol-lowering effect
3. Antioxidant free radical effect
4. Increases Vein Tone
5. Anti-osmosis and detumescence effect
6. Protective effect on ischemic injury
7. Protective effect on gastrointestinal tract
8. Anti-tumor effect
Part3. Clinical application
1. Coronary heart disease
Oral granules or tablets (10g per pack, 9g combined crude drug, 3g crude drug per tablet), 1 pack of granules each time, 2 times a day; or 2 tablets each time, 3 times a day , even served for 3 months. A total of 27 cases were observed, and the results: It has different degrees of improvement in the subjective symptoms of patients, and the total effective rate is 73%.
2. Cerebral edema
Add 6-18g of salsaponin, add 50ml of 10% glucose solution, and infuse daily (twice), the course of treatment is 5-7 days (up to 10 days in some cases), 3-4 days for children. A total of 45 patients with benign intracranial hypertension after brain trauma and cerebral edema after brain surgery were treated, and the total effective rate was 91%. It is also reported to use sodium aescinate, which is an extract of Sala seed, 5-10 mg per day for adults, no more than 25 mg per day, and 0.1-0.2 mg/kg for children, dissolved in 5-10 ml of 0.9% sodium chloride injection, Intravenous injection was used to treat 89 cases of traumatic swelling, 49 cases of anal canal edema and 39 cases of burns and plastic surgery patients, and the effective rates were 90.4%, 87.8% and 94.8% respectively.
3. Elderly bronchial asthma
Sala seed saponin, a traditional Chinese medicine extract, has a good curative effect on the treatment of senile bronchial asthma, and its side effects are lighter than those of hormones.
4. Radiation proctitis
Radiation proctitis is a relatively common complication in radiotherapy for pelvic tumors. Imodium combined with β-escin sodium for treatment has a synergistic effect and can significantly improve the symptoms of radiation proctitis.
5. Meniere's disease
Meniere's disease is mostly caused by evil criminals in the inner ear or weak viscera, lack of nourishment in the inner ear, or flooding of the inner ear with turbid phlegm and water. With β-escin sodium injection 25mg, diluted in glucose 5%, intravenous infusion, once a day achieved a good effect.
6. Peripheral facial neuritis
Aescin and dexamethasone were used to treat peripheral facial neuritis respectively, and the effective rate of the aescin group was 93%, which was better than that of the dexamethasone group.
7. Other therapeutic effects
Sodium aescinate is also clinically used to treat lumbar disc herniation, Japanese encephalitis, Guerrilla-Barr syndrome, burns, diabetic foot and other diseases.
